This paper concerns guidelines to support successful SSO analysis for Chip-PackageBoard systems. The procedures detailed address extraction and circuit simulation application of high node-count (N>100) frequency domain models. The focus of this paper is the low frequency portion, including DC, of the spectrum for broadband Sparameters. Frequency domain model extraction options and transient circuit simulation options were investigated and their interdependencies are discussed. These procedures apply to a broad class of extraction and transient circuit simulation tools typically applied to support SSO analysis. A high-speed digital board with 50 single-ended channels was applied as a test vehicle for guideline development.