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40 PCB Design Tips Every Designer Should Know

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19. Keeping Analog, Digital, and Power Domains Isolated Mixing analog, digital, and power circuits without proper isolation is a leading cause of noise, crosstalk, and performance loss, especially in mixed-signal systems such as sensor front-ends, audio, precision measurement, or wireless modules. Digital switching noise can easily couple into sensitive analog traces or reference nodes, while high-current power circuits can inject ripple and EMI into both digital and analog domains. Physical and electrical isolation at the PCB level is crucial for reliable system operation, low noise, and predictable analog performance. When And Where To Apply Apply isolation techniques at initial placement, before routing, and every time a new block is added or a design is revised. This is essential for mixed-signal PCBs (ADC/DAC, analog sensors, RF modules), motor control, power electronics, or any design requiring low noise, high dynamic range, or precision. Isolation of analog and digital components

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